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beta-Propiolactone
CASRN 57-57-8
Contents
0542
beta-Propiolactone; CASRN 57-57-8
Health assessment information on a chemical substance is included in IRIS only
after a comprehensive review of chronic toxicity data by U.S. EPA health
scientists from several Program Offices and the Office of Research and
Development. The summaries presented in Sections I and II represent a
consensus reached in the review process. Background information and
explanations of the methods used to derive the values given in IRIS are
provided in the Background Documents.
STATUS OF DATA FOR beta-Propiolactone
File On-Line 07/01/1991
Category (section) Status Last Revised
----------------------------------------- -------- ------------
Oral RfD Assessment (I.A.) no data
Inhalation RfC Assessment (I.B.) message 07/01/1991
Carcinogenicity Assessment (II.) no data 03/01/1994
_I. CHRONIC HEALTH HAZARD ASSESSMENTS FOR NONCARCINOGENIC EFFECTS
__I.A. REFERENCE DOSE FOR CHRONIC ORAL EXPOSURE (RfD)
Substance Name -- beta-Propiolactone
CASRN -- 57-57-8
Not available at this time.
__I.B. REFERENCE CONCENTRATION FOR CHRONIC INHALATION EXPOSURE (RfC)
Substance Name -- beta-Propiolactone
CASRN -- 57-57-8
The health effects data for beta-propiolatone were reviewed by the U.S.
EPA RfD/RfC Work Group and determined to be inadequate for the derivation of
an inhalation RfC. The verification status of this chemical is currently not
verifiable. For additional information on the health effects of this
chemical, interested parties are referred to the EPA documentation listed
below.
U.S. EPA. 1987. Reportable Quantity for beta-Propiolactone.
Prepared by the Office of Health and Environmental Assessment, Environmental
Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste
and Emergency Response, Washington, DC.
Agency Work Group Review -- 04/25/1991
EPA Contacts:
Please contact the Risk Information Hotline for all questions concerning this
assessment or IRIS, in general, at (513)569-7254 (phone), (513)569-7159 (FAX)
or RIH.IRIS@EPAMAIL.EPA.GOV (internet address).
_II. CARCINOGENICITY ASSESSMENT FOR LIFETIME EXPOSURE
Substance Name -- beta-Propiolactone
CASRN -- 57-57-8
Not available at this time.
_VI. BIBLIOGRAPHY
Substance Name -- beta-Propiolactone
CASRN -- 57-57-8
Last Revised -- 07/01/1991
__VI.A. ORAL RfD REFERENCES
None
__VI.B. INHALATION RfD REFERENCES
U.S. EPA. 1987. Reportable Quantity for beta-Propiolactone.
Prepared by the Office of Health and Environmental Assessment, Environmental
Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste
and Emergency Response, Washington, DC.
__VI.C. CARCINOGENICITY ASSESSMENT REFERENCES
None
_VII. REVISION HISTORY
Substance Name -- beta-Propiolactone
CASRN -- 57-57-8
-------- -------- --------------------------------------------------------
Date Section Description
-------- -------- --------------------------------------------------------
07/01/1991 I.B. Inhalation RfC message on-line
07/01/1991 VI. Bibliography on-line
03/01/1994 II. Carcinogenicity assessment now under review
VIII. SYNONYMS
Substance Name -- beta-Propiolactone
CASRN -- 57-57-8
Last Revised -- 07/01/1991
57-57-8
2-Oxetanone
beta-Propiolactone
beta-PROPIOLAKTON [Czech]
beta-PROPIONOLACTONE
beta-PROPROLACTONE
Betaprone
BPL
Caswell No. 709
EPA Pesticide Chemical Code 010901
HSDB 811
HYDRACRYLIC ACID beta-LACTONE
Hydracrylic acid, beta-lactone
NSC-21626
Propanoic acid, 3-hydroxy-, beta-lactone
Propanolide
Propiolactona [Spanish]
Propiolactone
Propiolactonum [Latin]
Propiolattone
1,3-PROPIOLACTONE
2-OXETANONE
3-HYDROXYPROPIONIC ACID LACTONE
3-PROPANOLIDE
3-PROPIOLACTONE
Last updated: 5 May 1998
URL: http://www.epa.gov/iris/SUBST/0542.HTM
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