Reactions that yield
Carboxylic Acid Derivatives
For each of the reactions on the left, predict the major organic product. Pay particular attention to the regiochemistry and stereochemistry of the reaction.Click the mouse on the reactant molecule to view the answer;
click on the reagent to briefly review the reaction.
The reaction of a carboxylic acid with an alcohol in the presence of acid will yield the corresponding carboxylate ester (Fischer esterification).
The reaction of an acid halide with an amine will yield the corresponding amide. In this example, the N,N-disubstituted amide is formed.
The reaction of a carboxylic acid with thionyl chloride will convert the acid into the corresponding acid chloride.
The reaction of an acid anhydride with an alcohol will result in the acylation of the alcohol and the formation of a carboxylic ester.
The reaction of a carboxylic acid with an alcohol in the presence of acid will yield the corresponding carboxylate ester (Fischer esterification).
The reaction of an acid halide with an amine will yield the corresponding amide.
The reaction of a carboxylic acid with thionyl chloride will convert the acid into the corresponding acid chloride.
The reaction of an acid anhydride with an alcohol will result in the acylation of the alcohol and the formation of a carboxylic ester.
