Aldol Condensation Reactions

For each of the reactions on the left, predict the major organic product. Pay particular attention to the regiochemistry and stereochemistry of the reaction.

Click the mouse on the reactant molecule to view the answer;

click on the reagent to briefly review the reaction.

Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone. In base, dehydration to the a-b-usaturated carbonyl is slow. 

























Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone.   In base, dehydration to the a-b-usaturated carbonyl is slow.






























Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone.   In base, dehydration to the a-b-usaturated carbonyl is slow.































Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone.   In base, dehydration to the a-b-usaturated carbonyl is slow.




























Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone.   In base, dehydration to the a-b-usaturated carbonyl is slow.




























Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone.   In base, dehydration to the a-b-usaturated carbonyl is slow.





























Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone.   In base, dehydration to the a-b-usaturated carbonyl is slow.





























Simple aldehydes and ketones possessing a-hydrogens will enolize in acid or base and the enolate anion which is formed will attack a second carbonyl compound to form a b-hydroxy aldehyde or ketone.   In base, dehydration to the a-b-usaturated carbonyl is slow.