THE KEIDERLING GROUP

Recent Lectures by Tim Keiderling

2010       

1.      February – Tulane University Chemistry Seminar, "Protein folding starting from the ground up. Thermodynamic and kinetic spectroscopic studies of peptides."

2.      April – University of Tromso, Norway, Institute of Theoretical Chemistry, " Protein and peptide conformational studies using vibrational spectra. Examples of site specific structure and dynamics with isotope labeling."

3.      August – 2nd VOA and Biological Raman conference, SUNY Albany, “Biopolymer conformational studies with vibrational circular dichroism, a review.”

2009       

1   March-PittCon, Chicago, Bob Snyder Memorial Symposium, Vibrational Spectroscopy of Macromolecules: From Polymers to Biology, "Peptide Vibrational Spectral Analysis Using Selective Isotopic Labeling. Experimental and Computational Results"

2.   April-Illinois Institute of Technology, Department Seminar, "Biopolymer conformational studies with vibrational circular dichroism.”

3.  August-- University of Brescia CD2009 and ISBC (International Symposium on Biological Chirality)-plenary lecture--"Circular dichroism and biochemical applications, conformational and time dependent studies."

 

2008       

1.      March—PittCon 2008, New Orleans, Williams Wright Award Symposium, “Peptide Conformation with vibrational spectroscopy and site selective resolution using isotope labeling”

2.      April—Rutgers University Newark, Chemistry Seminar "Site-specific folding and structure studies of peptides using isotopic labeling with vibrational spectroscopy"

3.      July – Current Trends in theoretical Chemistry V, Jagellonian Univ., Krakow, Poland, "Enhanced resolution of spectra and coupling for peptide vibrational spectra using an old technique, experimental and computational results with selective isotopic labeling."

4.      July – University of Warsaw, Chemistry Seminar, "Conformational studies of peptides using vibrational spectra. Equilibrium and kinetic analyses with site-specific resolution enabled by isotopic substitution."

5.      July – Robert Koch Institute, Berlin, Seminar, "Protein folding starting from the ground up. Thermodynamic and kinetic spectroscopic studies of peptides."

6.      August - 1st  International Conference on Vibrational Optical Activity (VOA1) , Manchester, U.K. Plenary Lecture.”Biopolymer conformational studies with vibrational circular dichroism.”

7.      October—FACSS, Reno 2008, VCD Symposium: "Vibrational Circular Dichroism: Evolution from Instrument Development to Biopolymer Applications. 30+ years and growing"

8.      November—Southeast Regional ACS Meeting, Nashville: " Biopolymer Applications of Vibrational Circular Dichroism "

2007       

 

1.   January- Oakland University, MI, Chemistry Dept. Informal seminar, “Enhanced structural insight for peptides and protein folding with circular dichroism.”

2.   March  - Vibrational Spectroscopy Research Symposium Series, Thermo-Fisher-Nicolet, Princeton, NJ "Use of isotope substitution for site specific structural insight in peptides with IR spectroscopies"

3.   June – ICAVS, International Confereence on Advanced Vibrational Spectroscopy, Corfu, Greece –(parallel session talk)- “Peptide Conformation with site selective resolution using isotope labeling and temperature jump IR spectroscopy”

4.   September—International CD Conference, Groningen, NL, (Key-note Lecture) “Peptide Conformation with site selective resolution using isotope labeling and vibrational CD”

2006                                       

 

1. April—ACS St. Louis Award Symposium, University of Missouri St. Louis, honoring Jim Chickos, 2006 Award winner, Plenary Lecture: "Isotopic substitution, conformational variation, spectroscopy and theoretical modeling, held together by thermodynamics."

2. May—University of Frankfurt, Institute of Biophysics Seminar “Enhanced structural information from IR with circular dichroism. Biopolymer and protein folding example”

3. May – Ruhr University, Bochum, Germany –Institute of Biophysics and SFB 642 (two seminar)

a. SFB Seminar--" Enhanced structural information from IR with circular dichroism. Biopolymer and protein folding example "

b. Institute student seminar- ”Isotopic labeling to determine site-resolved conformational properties of peptides with vibrational spectra”—pedagogically extended

4. September—VCD Users group meeting, at Annual FACSS Meeting, Orlando FL, sponsored by BioTools--“VCD Studies of Peptides with Isotopic Labeling Examples”

5. December - Vibrational Spectroscopy Research Symposium Series, Thermo-Fisher User Group, Downers Grove, IL "Use of isotope substitution for site specific structural insight in peptides with IR spectroscopies"

2005       

1.      January – University of Freiburg, Biophysics Seminar, “Applications of Vibrational and Electronic Optical Spectroscopy in Protein and Peptide Structure and Folding Analyses”

 

2.      February -- University of Southern California, Physical and Biological Chemistry Seminar, “Site-resolved experimental and theoretical structure and folding studies of isotopically labeled peptides with vibrational spectra”

 

3.      February—University of Wisconsin—Theoretical Chemistry Institute Seminar , “Site-resolved experimental and theoretical structure and folding studies of isotopically labeled peptides with vibrational spectra”

 

4.      March – University of Padova, Dipartimento di Chimica, Institute for Biopolymer Research, CNR, seminar—“Taking optical spectroscopy to the (structural) limit for peptide and protein applications with isotopic labeling”

 

5.      April – Eotvos University, Budapest – two research seminars (Dept. and Peptide Inst)

a. "Vibrational circular dichroism (VCD) enhancing infrared spectroscopy for conformational analyses.  Methods and Theory for Biopolymers"

 

b. ”Site-resolved experimental and theoretical structure and folding studies of isotopically labeled peptides with vibrational spectra”

 

6.      April -- Prague National Czech and Slovak Conference on Biologically Active Peptides, 9th, Invited plenary lecture "Site-resolved structural studies of isotopically labeled peptides with infrared spectra"

 

7.      August—ICAVS Conference, Lake Delavan, Wisconsin, invited lecture “b-hairpin peptides with isotopic labeling. Theoretical and experimental IR results”

 

8.      September—ECSBM 2005 Meeting, Aschaffenburg, Germany, “b-hairpin peptides with isotopic labeling. Theoretical and experimental IR results”

 

9.      November—University of Florida, Theoretical Chemistry Department Seminar --“Site-resolved experimental and theoretical structure and folding studies of isotopically labeled peptides with vibrational spectra”

 

10.    December—“Molecular spectroscopies and energy functions in the determination of macromolecular structure” Symposium in honor of Sam Krimm’s 80th Birthday, University of Michigan, Physics Dept.-- “Site-resolved spectral studies of isotopically labeled peptides with vibrational spectra” (cancelled due to flight problem)

 

Pedagogical:

1.  March – University of Padova, Dipartimento Chimica—series of 8 Lectures in Bio-organic curriculum—"Spectroscopic techniques for peptide and protein structural analyses" (emphasis IR, Raman,CD, and VCD for peptide chemists)

 

2.  October—FACSS Meeting, Quebec, Canada, Workshop, “Biological Infrared and Raman Spectroscopy”—8 hours of lectures on methods and applications

 

2004       

1.      October - Charles University, Prague, Institute of Physics, Biophysics Seminar “Site-resolved structural and dynamic folding studies of isotopically labeled peptides and proteins with vibrational spectra”

 

2.      October – Institute for Chemical Technology, Prague, Analytical Chemistry Seminar “Applications of Vibrational and Electronic Optical Spectroscopy in Protein and Peptide Structure and Folding Analyses”

 

3.      November –Warrick University, MOAC Seminar, “Applications of Vibrational and Electronic Optical Spectroscopy in Protein and Peptide Structure and Folding Analyses”

 

4.      November – Leeds University, Asbury Center Seminar, “Taking optical spectroscopy to the (structural) limit for peptide and protein applications with isotopic labeling”

 

5.      December – Ludwig-Maximillian University Munich, BMO Theoretical Biophysics Seminar, “Site-resolved experimental and theoretical structure and folding studies of isotopically labeled peptides with vibrational spectra”

 

Tutorial:  April - Film lecture on "Infrared spectroscopic Applications in biological Systems" for University of the Air, Japan, Filmed at UIC, April 2004, Video segment presented on Japanese Educational TV in 2005, archival film available from video library.

2003       

           1.    March -- Northwestern University, Physical Chemistry Seminar, "Site-specific conformational studies of peptides with vibrational spectroscopy and isotopic labeling"

 

           2.   May - University of Fribourg (Switzerland), Chemistry Seminar - "Conformational studies of peptides and proteins with optical spectroscopy"

 

           3.   May - University of Zurich, Physical Chemistry Seminar, "Site-specific conformational studies of peptides with vibrational spectroscopy and isotopic labeling"

 

           4.   May-- Infrared Spectrsocopy of Proteins Workshop.  University of Freiburg. (Ger.) "Understanding Details of proteins vibrational spectra. Theoretical simulation of IR and VCD spectra of isotopically labeled peptides, helices and hairpins"

 

           5.   June -- Symposium on Dynamics of Life Processes, Danish Technical University, Lyngby, DK "Peptide Vibrational Spectra: Understanding Details by Theoretical Simulation of Experimental IR and VCD Spectra of Isotopically Labeled Sequences"

 

           6.   June -- Scandinavian Mini-Symposium on Circular Dichroism - Applications in Chemistry and Biology, Pharmaceutical University of Denmark, Copenhagen. "Electronic and vibrational Circular Dichroism studies of peptide and protein conformation and folding as a complement to other spectroscopic techniques"

 

           7.   July - IUPAC  International  Discussion  Conference   on   the Spectroscopy of Partially Ordered Macromolecular Systems. Institute of Macromolecular Chemistry,  Prague, "Partially folded peptides and proteins, optical spectroscopy studies."

 

           8.   August -- ICAVS-2, 2nd International Conference on Advanced Vibrational Spectrsocopy, Nottingham, UK, Plenary lecture,  "Vibrational spectroscopic studies of peptide conformation and folding, enhanced by isotope effects and theoretical simulations."

 

           9.   September- International Conference on CD and Chiral Discrimination, Budapest Hungary - Keynote Lecture, "Site-specific CD, vibrational spectra with isotopic labeling, theory and experiment"

 

           10. November - Northern California SAS Meeting, Visiting Lecturer, "Vibrational circular dichroism and related spectroscopic methods. Techniques and applications,"

 

           11. November - ALZA Analytical Services Department Seminar, "Secondary structure determination with VCD, ECD and IR techniques"

 

           12. December - Thermo-Nicolet Corp. , Applications Lab Seminar, "Conformational studies of Peptides and proteins with vibrational spectroscopy"

           

2002

1. March - University of Puerto Rico, Rio Piedras, Department Seminar
-- "Protein and Peptide Conformational studies with Optical Spectra"

2. July - SPIE Meeting, Seattle, Session: Polarization Measurement, Analysis, and Applications V (AM103)
-- "Polarization Techniques in Optical Spectroscopy and Applications to Biopolymer Structure Studies"

3. July - Hinds Instruments, Hillsboro, OR --Lab seminar
-- "Polarization Modulation spectroscopy and biological applications"

4. September--Summer School on Circular Dichroism, University of Warick, Coventry, UK
- " IR absorbance and VCD for bio-macromolecule structure analysis"

           

2001

1. April – SAS Tour Speaker, St. Louis Section, Mallincrot Chemical
– "Protein and Peptide Conformational studies with Vibrational Spectra"

2. May - University of Iowa, Iowa City, Department Seminar
– "Protein and Peptide Conformational studies with Vibrational Spectra"

4. September -- European Conference on the Spectroscopy of Biological Molecules, Prague, Czech Rep.
- Spectroscopic characterization of b-sheet hairpins and 3-strand models" (short lecture)

5. September --Institute of Organic Chemistry and Biochemistry, Czech Academy of Science, Prague.
- "Experimental and theoretical spectroscopic characterization of a-helical and b-peptides with 13C isotope effects" (department seminar)

6. October - FACSS National Meeting, (participant in Meggars Award Symposium) Detroit
- "Computing peptide (and protein) IR and VCD spectra. Extra information from isotopic substitution"

7. October -- Illinois Institute of Technology, Department Seminar --
– "Protein and Peptide Conformational studies with Optical Spectra"

 

2000       

1. March - Physical chemistry of chirality Symposium at National ACS Meeting, San Francisco, Invited lecture,
"Localized conformational chirality in peptides with isotopic labeling VCD"

2. September- FACSS Annual Meeting, Nashville TN, Chiral techniques symposium,
"Protein and peptide conformations using vibrational circular dichroism, qualitative and quantitative studies"

3. September-Louisiana State University, Baton Rouge, LA, Department Seminar
--, "Protein and Peptide Conformational studies with Optical Spectra"

4. November - UK CD Users Group Annual Meeting/BBSRC Structural Biology Centre for Circular Dichroism Spectroscopy, Daresbury UK,
-- "Analysis of CD spectra of proteins and peptides using multi-variant techniques"

 

1999

1. February--Loras College, Chemistry Seminar,
"Protein Conformational studies" (recruiting talk)

2. April--National Cancer Institute (Frederick MD) Lab Seminar,
"Protein Conformational Studies with Optical Spectra"

3. July--Eppley Cancer Institute, University Nebraska Medical Center, Omaha,
"Protein and Peptide Conformational studies with Optical Spectra"

4. August--International CD Conference, Mierki, Poland, Invited Lecture,
"Peptide conformational chirality studies with VCD"

5. September--European Conference on the Spectroscopy of Biological Molecules,
a. Invited lecture, "Isotopic editing of VCD for site-specific conformational analyses"
b. Invited Multivariate Analysis Workshop short lecture, "Use of two-dimensional analyses to enhance spectral discrimination"

6. October--Symposium at PacifiChem (ACS+SAS regional meeting), Ontario, CA, "Protein and peptide folding studies with VCD"
-- "New Advances in Biomolecular Optical Spectroscopy"

7. February--SAS Short Course (1 Day, joint lecturer), Biophysical Society Meeting, in Baltimore
            --July, Repeat course again at Rocky Mountain Analytical Conference, in Denver
--" Biological Infrared Spectroscopy"

 

1998

1. February - North Carolina State University, Department of Chemistry Seminar,
"Protein and peptide conformational analysis using optical spectra"

2. March-Augustana College, Chemistry seminar,
"Protein conformation" (recruit)

3. August - European Congress on Molecular Spectroscopy XXIV, Prague, Czech Rep.
- "Vibrational circular dichroism"

4. August - American Chemical Society National Meeting, Boston, Symposium on Infrared Protein Studies, Lecture
"Protein conformations using optical spectra"

5. October - FACCS Meeting, Austin TX, Symposium on Chiral Spectroscopy, Lecture
"Computational simulation of peptide vibrational circular dichroism of peptides and model compounds for conformational determination."

 

 

1997

1. June - American Peptide Symposium, Nashville, TN (short talk, Conform Anal)
"Vibrational and Electronic Circular Dichroism studies of a-Me-Val oligomers."

2. August - Georgia State University, Department of Chemistry Seminar,
"Protein and peptide conformational analysis using optical spectra"

3. September - European Conference on the Spectroscopy of Biological Molecules, Madrid, (short lecture)
"Novel approaches to protein structural analyses using combination of optical spectroscopic methods"

4. September - International CD Conference, Pisa, Italy,
"Limitations and new applications of CD analyses of protein secondary structure (lecture)

5. September - Department of Organic Chemistry and Center for Biopolymer Research CNR, University of Padova, Italy - Department seminar,
"New peptide and protein conformational studies with optical spectroscopy"

6. October - FACSS Meeting, Providence, RI, Symposium: Modulation Spectroscopy.
"VCD and Protein Conformation"

7. November - Society for Applied Spectroscopy, Chicago Section, monthly meeting,
"VCD Methods and Applications"