Publications

Publications (most recent ones can be downloaded):  

1. Ishii, Y., Ashida, J., and Terao, T., 13C-1H dipolar recoupling dynamics in 13C multiple-pulse solid-state NMR. Chem. Phys. Lett., 1995. 246: p. 439-445.

2. Ishii, Y. and Terao, T., Determination of internuclear distances by observation of the Pake-doublet patterns using the MLEV-8 sequences with composite pulses. J. Magn. Reson. A, 1995. 115: p. 116-118.

3. Ishii, Y., Terao, T., and Kainosho, M., Relayed anisotropy correlation NMR: Determination of dihedral angles in solids. Chem. Phys. Lett., 1996. 256: p. 133-140.

4. Ishii, Y., Development and applications of solid state NMR methods. Doctor thesis, 1997.

5. Ishii, Y., Terao, T., and Hayashi, S., Theory and simulation of vibrational effects on structural measurements by solid state NMR. J. Chem. Phys., 1997. 107: p. 2760-2774.

6. Hirao, K., Ishii, Y., Terao, T., Kishimoto, Y., Miyatake, T., Ikariya, T., and Noyori, R., Solid-state NMR study of poly(phenylacetylene) synthesized with a Rhodium Complex Initiator. Macromolecules, 1998. 31: p. 3405-3408.

7. Ishii, Y., Hirao, K., Terao, T., Terauchi, T., Oba, M., Nishiyama, K., and Kainosho, M., Determination of peptide f angles in solids by relayed anisotropy correlation NMR. Solid State Nucl. Mag. Reson., 1998. 11: p. 169-175.

8. Ishii, Y. and Terao, T., Manipulation of nuclear spin Hamiltonians by rf-field modulations and its applications to observation of powder patterns under magic-angle spinning. J. Chem. Phys., 1998. 109(4): p. 1366-1374.

9. Balbach, J.J., Ishii, Y., Antzutkin, O.A., Leapman, R.D., Rizzo, N.W., Dyda, F., Reed, J., and Tycko, R., Amyloid fibril formation by Ab16-22, a seven-residue fragment of the Alzheimer's b-Amyloid peptide, and structural characterization by solid state NMR. Biochemistry, 2000. 39(45): p. 13748-13759.

10. Ishii, Y. and Tycko, R., Multidimensional heteronuclear correlation spectroscopy of a uniformly 15N- and 13C labeled peptide crystal: Toward spectral resolution, assignment, and structure determination of oriented molecules in solid state NMR. J. Am. Chem. Soc., 2000. 122(7): p. 1443-1455.

11. Ishii, Y. and Tycko, R., Sensitivity enhancement in solid state 15N NMR by indirect detection with high-sped magic angle spinning. J. Magn. Reson., 2000. 142: p. 199-204.

12. Tycko, R., Blanco, F.J., and Ishii, Y., Alignment of biopolymers in strained gels: A new way to create detectable dipole-dipole couplings in high-resolution biomolecular NMR. J. Am. Chem. Soc., 2000. 122: p. 9340-9341.

13. Ishii, Y., 13C-13C dipolar recoupling under very fast magic angle spinning in solid-state NMR: Applications to distance measurements, spectral assignments, and high-throughput secondary-structure elucidation. J. Chem. Phys., 2001. 114: p. 8473.

14. Ishii, Y., Balbach, J.J., and Tycko, R., Measurement of dipole-coupled lineshapes in a many-spin system by constant-time two-dimensional solid state NMR with high- speed magic-angle spinning. Chem. Phys., 2001. 266(2-3): p. 231-236.

15. Ishii, Y., Markus, M.A., and Tycko, R., Controlling residual dipolar couplings in high-resolution NMR of proteins by strain induced alignment in a gel. J. Biomol. NMR, 2001. 21: p. 141-151.

16. Ishii, Y., Yesinowski, J.P., and Tycko, R., Sensitivity enhancement in solid-state C-13 NMR of synthetic polymers and biopolymers by H-1 NMR detection with high-speed magic angle spinning. J. Am. Chem. Soc., 2001. 123(12): p. 2921-2922.

17 Pekotova, A., Ishii, Y., Balbach, J. J., Antzutkin, O. A., Leapman, R. D., Delaglio, F. and Tycko, R.  A structural model for Alzheimer's b-amyloid peptide fibrils based on experimental constraints from solid-state NMR spectroscopy. Proc. Natl. Acad. Sci. U.S.A. 2002 99, 16742-16747.

18 Ishii, Y., Chimon, S. and Wickramasinghe, N. P.  A new approach in 1D and 2D 13C high resolution solid-state NMR spectroscopy of paramagnetic organometallic complexes by very fast magic-angle spinning. J. Am. Chem. Soc. 2003 125, 3438-3439.

19.     Wickramasinghe, N. P., Shaibat, M. & Ishii, Y. Enhanced Sensitivity and Resolution in 1H Solid-State NMR Spectroscopy of Paramagnetic Complexes under Very Fast Magic Angle Spinning. J. Am. Chem. Soc. 127, 5796-5797 (2005).

20.     Chimon, S. & Ishii, Y. Capturing intermediate structures of Alzheimer's b-amyloid, Ab(1-40), by solid-state NMR spectroscopy. J. Am. Chem. Soc. 127, 13472-13473 (2005).

21.     Wickramasinghe, N.P., Shaibat, M. & Ishii, Y. Enhanced Sensitivity and Resolution in 1H Solid-State NMR Spectroscopy of Paramagnetic Complexes under Very Fast Magic Angle Spinning. J. Am. Chem. Soc. 127, 5796-5797 (2005).

22.     Ishii, Y. & Wickramasinghe, N.P. 1H and 13C high-resolution solid-state NMR of paramagnetic compounds under Very Fast Magic Angle Spinning. in Modern Magnetic Resonances (ed. Webb, G.) (Springer, Berlin, 2006).

23.     Wickramasinghe, N.P. & Ishii, Y. Sensitivity enhancement, assignment, and distance measurement in 13C solid-state NMR spectroscopy for paramagnetic systems under fast magic angle spinning. J. Magn. Reson. 181, 233-243 (2006).

24.     Chen, X., Xu, Z.H., Li, X., Shaibat, M.A., Ishii, Y. & Ruoff, R.S. Structural and Mechanical Characterization of Platelet Graphite Nanofibers. Carbon 45, 416-423 (2007).

25.     Chimon, S., Shaibat, M.A., Jones, C.R., Calero, D.C., Aizezi, B. & Ishii, Y. Evidence of fibril-like ß-sheet structures in neurotoxic amyloid intermediate for Alzheimer's ß-amyloid. Nature Structural & Molecular Biology 14, 1157-1164 (2007).

26.     Kotecha, M., Wickramasinghe, N.P. & Ishii, Y. Efficient low-power heteronuclear decoupling in 13C high-resolution solid-state NMR under fast magic angle spinning. Magnetic Resonance in Chemistry 45, S221-230 (2007).

27.     Shaibat, M.A., Casabianca, L.B., Wickramasinghe, N.P., Guggenheim, S., de Dios, A.C. & Ishii, Y. Characterization of polymorphs and solid-state reactions for paramagnetic systems by 13C solid-state NMR and ab-initio calculations. J. Am. Chem. Soc 129, 10968-10969 (2007).

28.     Wickramasinghe, N.P., Kotecha, M., Samoson, A., Past, J. & Ishii, Y. Sensitivity enhancement in 13C solid-state NMR of protein microcrystals by use of paramagnetic metal Ions for optimizing 1H T1 relaxation. J. Magn. Reson. 184, 350-356 (2007).

29.     Wickramasinghe, N.P., Shaibat, M. & Ishii, Y. Elucidating connectivity and metal binding structures in unlabeled paramagnetic systems by 13C high-resolution solid-state NMR spectroscopy under fast magic angle spinning. J. Phys. Chem. B. 111, 9693-9696 (2007).

30.     Wickramasinghe, N.P., Shaibat, M., Casabianca, L.B., de Dios, A.C., Harwood, J.S. & Ishii, Y. Progress in 13C and 1H solid-state NMR for paramagnetic systems under very fast MAS. J. Chem. Phys. 128, 52210 (2008).

31.     Cai, W., Pine, R.D., Stadermann, F., Park, S., Shaibat, M., Ishii, Y., Yang, D., Velamakanni, A., An, S.J., Stoller, M., An, J., Chen, D.M. & Ruoff, R.S. Synthesis and solid-state NMR structural characterization of 13C-labeled graphite oxide. Science 321, 1815-1818 (2008).

32.     Wickramasinghe, N. P., Parthasarathy, S., Jones, C. R., Bhardwaj, C., Long, F., Kotecha, M., Mehboob, S., Fung, L. W. M., Past, J., Samoson, A. & Ishii, Y. Nanomole-scale protein solid-state NMR by breaking intrinsic H-1 T-1 boundaries. Nature Methods 6, 215-218, doi:10.1038/nmeth.1300 (2009).

33.     Shaibat, M., Casabianca, L. B., Siberio-Pérez, D. Y., Matzger, A. J. & Ishii, Y. Distinguishing polymorphs for paramagnetic copper(II) phtalocyanine complexes by 13C and 1H solid-state NMR under very fast MAS. J. Phys. Chem. B 114, 4400-4406 (2010).

34.     Casabianca, L. B., Shaibat, M., Cai, W., Park, S., Piner, R., Ruoff, R. S. & Ishii, Y. NMR-based structural modeling of graphite oxide using multi-dimensional 13C solid-state NMR and ab-initio chemical shift calculations. J. Am. Chem. Soc. 132, 5672-5676 (2010).

35.     Parthasarathy, S., Long, F., Miller, Y., Xiao, Y., Thurber, K., McElheny, D., B., M., Nussinov, R. & Ishii, Y. Molecular-level examination of Cu2+ binding structure for amyloid fibrils of 40-residue Alzheimer's beta by solid-state NMR spectroscopy. J. Am. Chem. Soc. (In press).

 

 

 

Selected Presentations by the PI:  (# are talks  * are invited talks)

1.*     Y. Ishii. Solid-state NMR study of amyloid proteins and paramagnetic systems. in Pachifichem 2005. 2005. Honolulu, Hawaii.

2.*     Y. Ishii. Solid-state NMR studies of amyloid peptides and paramagnetic systems. in Solid-state NMR and material conference. 2005. Kyoto, Japan.

3.*     Y. Ishii. Solid-state NMR studies of Alzheimer's disease-related amyloid peptides and recent progress in solid-state NMR for paramagnetic systems. in Riken GSC, NMR seminar. 2005. Yokohama, Japan.

4.#     Y. Ishii, N.P. Wickramashinge, M. Shaibat, C. Jones, and S. Chimon. Solid-state NMR studies of amyloid peptides and paramagnetic systems. in 46 th Experimental NMR conference. 2005. Providence, Rhode Island.

5.*     Y. Ishii. High-resolution 13C and 1H solid-state NMR of paramagnetic systems under very fast MAS and applications of solid-state NMR to biological solids. in Rocky Mountain Conference. 2004. Denver.

6.*     Y. Ishii. Solid-State NMR of paramagnetic systems and amyloid peptides. in MUACC. 2004. Columbus, OH.

7.*     Y. Ishii. 13C and 1H high-resolution solid-state NMR of paramagnetic systems under very fast MAS and solid-state NMR studies of amyloid peptides. in ISMAR 2004. 2004. Ponte Vedra Beach, FL.

8.*     Y. Ishii. Resolution, sensitivity, and assignments in 13C and 1H solid-state NMR of paramagnetic systems by very fast MAS and solid-state NMR studies of amyloid peptides. in 36th ACS central regonal meeting. 2004. Indianapolis, IN.

9.*     Y. Ishii. Solid-state NMR study of paramagnetic systems and amyloid peptides. in Chemistry seminar at Michigan State University. 2004. Lansing, MI.

10.#   Y. Ishii, N.P. Wickramasinghe, and S. Chimon A new approach in 1D and 2D 13C high-resolution solid-state NMR of paramagnetic organometallic complexes by very fast magic-angle spinning. in 44 th Experimental NMR Conference. 2003. Savannah, GA.

11.#   Y. Ishii, Development of new solid-state NMR methods under fast magic angle spinning. in MUACC. 2002. Pittsburgh, PA.

12.#   Ishii, Y. New approaches in solid-state NMR for resolution and structural elucidation of complex systems. in CANMRDG. 2002. Univesrsity of Nortre Dome, Notre Dame, Indiana.

13.*   Ishii, Y. Development and applications of novel solid-state NMR methods: Probing non-crystalline structures of biomolecules and novel materials. in Chemistry Seminar. 2001. Illinois Institute of Technology

14.#   Ishii, Y. and R. Tycko. Sensitivity enhancements, signal assignments, and structure measurements for biomolecular solid state NMR. in Pachifichem 2000. 2000. Honolulu, Hawaii.

15.*   Ishii, Y. and R. Tycko. Sensitivity-enhanced solid state NMR by proton detection with high speed MAS: Application to bio- and synthetic polymers. in American Chemical Society National Meeting. 2000. San Francisco.

16.#   Ishii, Y. and R. Tycko. Sensitivity-enhanced solid state NMR by proton detection with high speed MAS. in 41st Experimental NMR Conference. 2000. Asilomar, CA.

17.     Ishii, Y. and R. Tycko. New solid state NMR method for structural determination of fully labeled oriented proteins. in 40 th Experimental NMR conference. 1999. Orlando.

18.     Ishii, Y. and T. Terao. Manipulation of nuclear spin Hamiltonian by rf-field modulation and its application to observation of powder patterns under magic angle spinning. in 39th Experimental NMR Conference. 1998. Asilomar, CA.

19.#   Ishii, Y. and T. Terao. Determination of dihedral angles in solids: Relayed anisotropy correlation NMR. in NMR seminar. 1997. Chemistry Department, Colombia University, NY.

20.#   Ishii, Y. and T. Terao. Developments of new solid state NMR methods for elucidating structural information. in NMR seminar at MIT. 1997. Francis Bitter magnet laboratory, MIT.

21.*   Ishii, Y. and T. Terao. Developments of new solid state NMR methods for elucidation of structural information. in Workshop on solid-state NMR in structural biology. 1997. Philadelphia, PA.

22.#   Ishii, Y. and T. Terao. Relayed anisotropy correlation NMR: Determination of dihedral angles in solids. in The 28tth congress ampere on magnetic resonance and related phenomena,. 1996. Canterbury, UK.

23.     Ishii, Y. and T. Terao. Measurements of dipolar spectra for 13C-15N using the MLEV8/8R sequence with composite pulses and for 13C-1H using the combined use of the WIM-12/FSLG-2 sequence and MAS. in ISMAR. 1995. Sydney, Australia.

There are additional 7 poster presentations and 6 talks.